Russia uses ICBM against Ukraine for the first time as missiles hit Dnipro, Air Force says.

Editor’s note: The article was updated with the Air Force’s report about Russia using an intercontinental ballistic missile. This is a developing story.
Russian forces launched a large-missile missile attack early on Nov. 21, reportedly lifting Tu-95 bombers and MiG-31K Kinzhal carriers and attacking the central-eastern city of Dnipro.
Russia attacked Dnipro with a conventional intercontinental ballistic missile (ICBM), a Kh-47M2 Kinzhal air-launched ballistic missile, and seven Kh-101 cruise missiles, the Air Force said. Six of the Kh-101 missiles were reportedly shot down.
This marks the first instance of Russia using an ICBM in its war against Ukraine. The missile was launched from Astrakhan Oblast, a Russian region 740 kilometers (460 miles) from Dnipro, the Air Force said.
An industrial enterprise, two houses, and nine garages were damaged, and two fires broke out in the city, Governor Serhii Lysak said. A rehabilitation center for people with disabilities was damaged in the attack, Mayor Borys Filatov said.
Two people were reported as injured. A 57-year-old man was treated on the spot, and a 42-year-old woman was hospitalized, officials said.
Polish and NATO allies scrambled their fighter jets in Poland in response to the attack, a usual response during mass aerial strikes on Ukraine.
Elsewhere across the country, Russian attacks killed at least three people and injured at least 22 over the past day, including a child, authorities reported.
In Donetsk Oblast, a Russian attack against the village of Pershomarivka killed one person and injured two, Governor Vadym Filashkin reported. Six people were reportedly injured during an attack against the town of Kostiantynivka.
Russian attacks against Kherson Oblast overnight and on Nov. 20 killed one person and injured 10, including a child, according to Governor Oleksandr Prokudin. A 62-year-old woman was also killed during an attack against the Darivka village on the morning of Nov. 21, the governor said.
In Kharkiv Oblast, a 64-year-old woman was injured in an attack against the village Vysokyi, and two men aged 42 and 64 were wounded in strikes against the town of Kupiansk, Governor Oleh Syniehubov reported.
A civilian was injured during Russian attacks against the Krasnopillia community in Sumy Oblast, the regional military administration said.